Research Principal Scientist - Novo Nordisk - Måløv


Job description
Novo Nordisk is a protein-based, focused healthcare company. For the past 90 years Novo Nordisk has pioneered therapeutic proteins to address unmet medical needs. Today, more than 6,000 employees work with R&D across the globe.

About the department
The Structural biology department is an integral part of the Diabetes Protein Engineering function with the task of providing structure based design of therapeutic proteins and peptides with improved pharmacological and formulation properties for the treatment of diabetes.

We are 10 enthusiastic individuals located in Måløv, Denmark, with expertise within protein modelling, X-ray crystallography, small angle X-ray scattering and protein chemistry.

The job
As a key member of discovery research projects you will proactively utilize, communicate and leverage bio-structural information to guide the design of biopharmaceutical molecules within a multi-dimensional chemical and formulation space.


You will provide protein homology models, perform advanced data mining and analysis and apply molecular dynamics calculations in interpretation of experimental data such as NMR and SAXS with the ultimate goal of designing compounds with improved biological, physical and pharmacological properties.

You will have the opportunity to influence your own development and grow into a key role at the interface of between protein chemistry, structural biology, formulation and pharmacology.
Desired Skills and Experience
Qualifications
You hold a PhD in Computational Chemistry, modelling or a related discipline and have at least three years of post-doctoral experience. Previous experience from pharmaceutical industry would be a plus.

You have expert knowledge of computational aspects of 3D molecular structure and design (such as protein homology modelling, MD simulations), preferably coupled with hands-on experience in SAXS or NMR. Additional relevant skills within advanced large scale data analysis techniques and protein protein docking are highly desirable, as is familiarity with commercial molecular modelling and data-mining software.



You are fluent in English and good to share results and interact with scientist of different disciplines

You are enthusiastic about driving discoveries and have demonstrated scientific excellence by publication in peer reviewed journals and patents. You are skilled in extracting information and articulating clear and convincing hypotheses.

At Novo Nordisk, we strive for excellence. As a world leader in diabetes care and a major player in haemostasis management, growth hormone therapy and hormone replacement therapy, we offer our employees opportunities for continuous growth.
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